The aminoglycoside antibiotic neomycin has robust antibacterial properties, yet its clinical utility is curtailed by its nephrotoxicity and ototoxicity. The mechanism by which the polycationic ...

Living cells constantly exchange ions (i.e., charged particles) via the thin barrier that surrounds their interior, known as ...

Targeted degradation of membrane-associated proteins, which constitute a crucial class of drug targets implicated in diverse disease pathologies, has garnered considerable attention in chemical ...

Cells may generate their own electrical signals through microscopic membrane motions. Researchers show that active molecular processes can create voltage spikes similar to those used by neurons. These ...

Artificial cells created in the laboratory offer a wide range of potential applications. Until now, however, their membranes—unlike those of real cells—have been virtually impermeable. Researchers at ...

Scientists have long known that cellular membranes vary in thickness, but measuring those differences inside actual cells has been out of reach. Until now, scientists could only measure membrane ...

In every living cell, there are membranes—and in every membrane there are proteins, each of which acts as a chemical gatekeeper. Rather than passively letting ions pass in and out of the cell, these ...

‘Tiny biological batteries’ can change the cell membrane’s electrical properties – a discovery that has big implications for health, as many essential cellular processes hinge upon precise electrical ...

Cell membranes are the boundaries of living cells. They are made up of amphiphilic lipids, cholesterol, and membrane proteins arranged in a dynamic bilayer. They regulate signal transduction, ...