Researchers discovered that fedratinib promotes endoplasmic reticulum–mitochondria contact sites. The drug inhibits BRD4, ...

Cells behave like cities and organelles carry out infrastructural roles: mitochondria are powerhouses, the endoplasmic ...

Calcium (Ca 2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, has not ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

What is the endoplasmic reticulum? The endoplasmic reticulum is the single largest membrane-bound organelle found inside eukaryotic cells. Its complex structure containing tubules, sheets, and ...

Spinal cord injury often triggers a cascade of secondary damage that severely limits functional recovery, largely driven by ...

Cells behave like cities and organelles carry out infrastructural roles: Mitochondria are powerhouses, the endoplasmic reticulum serves as a transport ...

A fat signaling system controls the interface of cellular endoplasmic reticulum (ER) with early endosomes to regulate the shape and activity of mitochondria, and allow cells to survive periods of ...

Protein sorting in the secretory pathway is essential for cellular compartmentalization and homeostasis in eukaryotic cells. The endoplasmic reticulum (ER) is the biosynthetic and folding factory of ...