Nature

Vector-free DNA constructs improve transgene expression in C. elegans

Figure 1: Expression of reporter gene constructs derived from the gcy-5, lim-6 and lsy-6 genes. One potential explanation for our observations is that the vector backbone may dictate the packaging of ...
Labroots

Producing Recombinant Proteins with the Baculovirus Expression Vector System (BEVS)

Over the past three decades, baculovirus expression vector system (BEVS) has become one of the most powerful and robust methodologies for recombinant protein production. This system can express ...
ascopubs.org

Single vector multiplexed shRNA provides a non-gene edited strategy to concurrently knockdown the expression of multiple genes in CAR T cells.

An increase in serum choline levels to predict progression-free survival (PFS) in patients (pts) with advanced cancers receiving pembrolizumab. A phase I, dose-escalation study of ADG106, a fully ...
GEN

The Combination of Ubiquitous Chromatin Opening Element (UCOE®) Expression Technology with the CHOZN® Platform Reduces Resources and Cell Line Development Timelines

In biopharmaceutical manufacturing, the development of an expression system that stably produces high levels of desired recombinant protein can be a time consuming and resource-intensive process. In ...
GEN

A Novel Endotoxin-Free Microbial Expression System

Escherichia coli is widely considered the most cost-effective bacterial system for recombinant protein expression. Consequently, it is broadly used. Nonetheless, it has its limitations as an ...
JSTOR Daily

A Universal Expression/Silencing Vector in Plants

A universal vector (IL-60 and auxiliary constructs), expressing or silencing genes in every plant tested to date, is described. Plants that have been successfully manipulated by the IL-60 system ...