The proximal part of the small intestine, including duodenum and jejunum, is not only dedicated to nutrient digestion and absorption but is also a highly regulated immune site exposed to environmental ...

The pathogenesis of celiac disease (CeD) remains incompletely understood. Traditional diagnostic techniques for CeD include serological testing and endoscopic examination; however, they have ...

High blood levels of autoimmune antibodies directed against tissue transglutaminase are an indicator of celiac disease, though the most definitive way to diagnose celiac disease is by identification ...

Celiac disease is an autoimmune response to consuming gluten, a protein often found in wheat, barley, and rye. Once triggered, the immune system causes an inflammatory response, damaging the lining of ...

A new comprehensive atlas of cells fills gaps in knowledge on how different cells in the intestine act together to drive celiac disease, potentially opening new avenues for future therapeutic ...

Stained photomicrographs of small intestinal biopsies from newly diagnosed celiac disease patients showing marked architectural distortion that comprise total villous atrophy, crypt hyperplasia and ...

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes. That is wat ...