Michael B. Bottorff, PharmD: We’ve been using warfarin for atrial fibrillation and stroke prevention for quite some time, now. It’s an indirect acting anticoagulant. The way it works is that it blocks ...

In 2017, we have the advantage of, having available to us, 4 large clinical trials. All of the phase IV studies that have been published over the last few years review the use of novel oral ...

For patients with nonvalvular atrial fibrillation (AFib) who had no contraindications to taking oral anticoagulants, the use ...

For patients who are scheduled for surgery, warfarin therapy should be discontinued 5 to 6 days before the procedure. 26 In patients who are at high risk for developing blood clots, the clinician may ...

Findings address a known evidence gap and add to the clinical evidence base from randomised controlled trials and network meta-analyses to directly compare direct oral anticoagulants for stroke ...

RARITAN, NJ, Janssen Pharmaceuticals, Inc. announced today the U.S. Food and Drug Administration (FDA) has approved XARELTO® to reduce the risk of stroke and systemic embolism in patients with ...

Retrospective data support use of oral anticoagulants for death and MACE risk reduction in patients with end-stage kidney disease and nonvalvular atrial fibrillation who have an elevated CHA2DS2-VASc ...

A new study examined more than 5100 adults with nonvalvular AF who were starting oral anticoagulation therapy. Patients were divided into 4 groups, each with different baseline clinical ...

The US Food and Administration (FDA) has approved the Amplatzer Amulet left atrial appendage occluder (Abbott) to treat people with nonvalvular atrial fibrillation who are at increased risk for stroke ...

“To the best of our knowledge, this is the first study to have demonstrated the preventive effect of AF ablation on long-term AF-related cardiovascular events in very old patients with NVAF.” “We ...

Very elderly people with nonvalvular atrial fibrillation (Afib) got the same stroke prevention benefits from edoxaban (Savaysa) and apixaban (Eliquis), though one drug was associated with more major ...

Each month, The Clinical Advisor makes one new clinical feature available ahead of print. Don’t forget to take the poll. The results will be published in the next month’s issue. The American Heart ...