Pneumolysin, a key Streptococcus pneumoniae virulence factor, is a cholesterol-dependent cytolysin that creates pores in cholesterol-containing membranes, thus causing host cell lysis. Pneumolysin has ...

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against ...

Streptococcus pneumoniae is a major human pathogen and is known to be associated with increased risk of fatal heart complications including heart failure and heart attacks. As Streptococcus pneumoniae ...

Severe illness and even death are likely to result if you develop another respiratory infection after catching the flu. Now, however, a team of researchers has determined that if you reverse the order ...

Scientists from the University of Leicester have for the first time created a detailed image of a toxin - called pneumolysin - associated with deadly infections such as bacterial pneumonia, meningitis ...

Pneumococci are the most common cause of respiratory tract infections, such as otitis and sinusitis, as well as of severe infections like pneumonia and meningitis. A new study from Karolinska ...

Last fall investigators at the University of Texas Health Science Center at San Antonio demonstrated how infections triggered by Streptococcus pneumoniae could damage the heart, explaining why older ...

Scientists at the University of Liverpool have discovered a new and important function of a toxin produced by disease-causing bacteria that could have significant implications for future vaccine ...

Pneumococci are the most common cause of respiratory tract infections, such as otitis and sinusitis, as well as of severe infections like pneumonia and meningitis. A new study shows how the bacteria ...