Over the past decade, however, a wave of technological advances has begun to expand the druggable proteome. These include covalent inhibitors (such as sotorasib), chemical proteomics, and AI-enabled ...

Early prediction and identification of neurodegenerative diseases offers the best chance for prevention and treatment.

Researchers from the MPI of Biochemistry and the Technical University of Munich have discovered new diagnostic markers for multiple sclerosis (MS), a disease that affects 3 million people worldwide.

Development and validation of a gene expression signature based on RB1, PTEN, and TP53 in patients with metastatic hormone-sensitive prostate cancer (mHSPC).

A recent study posted to the medRxiv preprint server investigates the association between the circulating proteome and brain health. Study: The circulating proteome and brain health: Mendelian ...

A milestone in biology has been achieved thanks to artificial intelligence (AI) machine learning and applied physics. A new peer-reviewed study by researchers affiliated with Harvard John A. Paulson ...

Following on from his exposé of the dearth of specificity in our vocabulary surrounding the proteome and his emphasis that individual proteoforms should be the focus of our proteomic investigations, ...

Explore how proteomics transforms pharmaceutical R&D, from drug discovery to biomarker qualification and clinical development ...

A multicellular system isn’t a system just because it has many cells. The cells must be of different types. Indeed, a great many different cell types are needed. To distinguish as many cell types as ...

The cell-surface proteome is spatially dynamic and changes with the state of the cell, which in turn determines its activity in health and disease. As part of our In Focus on single-cell spatial ...