Scientists have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using a supercomputer. Their protocol ...

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat ...

“Insulin injections remain a daily burden for many patients,” said Associate Professor Shingo Ito. “Our peptide-based ...

Cyclic peptides derived from flaxseed, commonly known as cyclolinopeptides or linusorbs, represent a unique class of naturally occurring bioactive compounds. Their cyclic structure confers enhanced ...

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat ...

A long-held dream in medicine is nearing reality as researchers at Kumamoto University have successfully developed insulin ...

BEIJING, Jan. 8, 2025 /PRNewswire/ -- In a recent achievement, DP Technology's hit discovery platform RiDYMO® has successfully designed a cyclic peptide targeting β-catenin, a historically ...

Orbis Medicines emerged from stealth Feb. 29 with $28 million in seed funding. The company is the latest launched to turn cyclic peptide molecules into orally available drugs that could replace ...

Research reveals an innovative insulin pill that successfully delivers insulin orally, improving treatment options for ...

Researchers at the Tokyo Institute of Technology say they have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic ...

Scientists at Tokyo Institute of Technology have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using ...