Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...
Ruggiano and Ramadan 4 provide an overview of the mechanisms dedicated to removing replication obstacles, such as proteins covalently or tightly bound to DNA. Their work discusses how molecular ...
If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...
Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...
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